ساحة حوار الـpharmacology

[a_fouda2]

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"ربنا لا تزغ قلوبنا بعد إذ هديتنا وهب لنا من لدنك رحمة إنك أنت الوهاب"

اللهم آمين

شكرًا
جزاكم الله خيرًا يا دكتورة

محاضرة الفارما


http://www.mediafire.com/?i31rpo47j3fiw3m

شكرًا يا مرسي باشا

[Moonlight]

جزاكم الله خيرا جميعا

[محمد_على_سلام]

محاضرة الفارما

http://www.mediafire.com/?i31rpo47j3fiw3m

جزاك الله كل خير
شكرا يا حمودى

[حموودي النمر]

I got a permanent ban on the board for being vulgar, reflecting the atmosphere where I am living

[محمد_على_سلام]

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"ربنا لا تزغ قلوبنا بعد إذ هديتنا وهب لنا من لدنك رحمة إنك أنت الوهاب"

آآآآآمين
جزاك الله كل خير

[a_fouda2]

السلام عليكم ورحمة الله وبركاته

دي كل اسئلة الفارما اللي كانت في موضوع ال friday sheets قبل كده
أنا جمعتها عشان نقرأها ان شاء الله بعد ما نخلص مذاكرة ( اذا خلصنا )

First sheet :

True and false:

1- pharmacodynamics is what the drugs do to body . (true)
2- bulk transfer mechanism depends lipid solubility. (false)
3- exocytosis is the invagination of extracellular substances as vesicles. (false)
4- If the drug is lipid soluble , the absorption rate is increased. (true)
5- Vancomycin is absorbed from GIT to systemic circulation to give its effect. (false)
6- Atropine decreases GI motility. (true)
7- Tetracycline binds strongly with Ca +2. (true)


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Second sheet

True or False

1-drug which has very high water solubility are good absorbed (F)

2- a drug taken after meal is often more slowly absorbed (T)

3- conc of anti malarial quinacrine in the spleen is more than in plasma (F)


Complete

1- timolol eye drops is used in treatment of glucoma and can produce broncho spasm in asthmatic patient as side effect

2- methotrexate is administered intrathecally in ttt of childhood leukemia
3- biotransformation is conversion of lipid soluble drug to more polar compound in order to be excreted

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Third sheet

Choose the correct answer:

- Histaminic antagonists produce all of the following except diarrhea
( sedation - prevention of vomiting - diarrhea)
- Sympathetic nervous system innervate all of the following except ciliary muscle
( adrenal medulla - sweat glands - ciliary muscle)
- B1 receptors present in heart
(small muscles - heart -adipose tissue)

Complete:

- Agonists can produce submaximal effect and never reaches the maximal effect called partial agonists
- Continued stimulation of cells with agonists result in state of desenstization or down regulation
- Adrenergic transmission is clasiified chemically to catecholamines & non catecholamines

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Fourth sheet

Complete the following :

1- Vasopressor sympathomimetics are used in certain hypotensive state and as nasal decongestants

2- (Privine and (Afrin) have few side effects as rebound congestion and rise in blood pressure

3- Dobutamine has greater inotropic than chronotropic effects

4- effect of epinephrine in ,mtabolism Increases release of free fatty acid from adipose tissue and elevate level of cholesterol, phospholipids and lipoprotein.

5- Dopamine is used for the correction of haemodynamic imbalances present in the shock syndrome due to acute myocardial infarction

6- Amphetamines have a high potential for abuse and dependence.

7- methylphenidate used for narcolepsy and in attention deficit hyperactivity disorder (ADHD).

8- Fenfluramine cause release of serotonin & may increase glucose utilization .

9- Phenmetrazine, phentermine and mazindol act through adrenergic and/or dopaminergic pathways.

10- Pheochromocytoma >>>> rare form of hypertension caused by tumor of adrenal medulla tissues.

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Fifth sheet

1- what is the side effect of prazosine ? how we can solve it ?

side effect : first dose effect can lead to
coma(syncope) after 2 hrs after administration
we can solve it by administration before bed time

2- why B- blocker is contra-indicated for asmatic patient ?

if we use non specific B- blockers it cause block B2 receptors and cause bronchospasm , so we prefer selective B1 blocker .


3- why we don't use ACH as drug ?

it rapidly hydrolysed by enzyme cholinestrase and have diverse effects in human body.


Complete :

4- Methylergonovine (mehergine) and ergonovine (ergometrine) cause contraction for uterus S. muscles so used as treatment for hemorrhage after labor.

5- Decrease in M1 receptors cause Alzheimer Disease.


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Sixth sheet

1 ) why we use mathacholine in diagnosis of
pheochromocytoma ?

Methacholine is a purely muscarinic drug in case of normal person will cause hypotention
but in the case of Pheochromocytoma : will cause
hypertention because stimulate E , NE from adrenal medulla
that leads to hypertention

2)what is the effect of muscarinic antagonists on

cardiovascular system ?

The first effect produced on the heart is paradoxically bradycardia for few seconds

slightly larger doses produce expected tachycardia
due to block of cardiac muscarinic activity

why we use L-dopa with dopa decarboxylase in the periphery in treatment of parkinsonism ?


As L-dopa pass blood brain barrier but dopamine can not pass it
but L-dopa is hydrolyzed by dopa decarboxylase to form dopamine so administration of L-dopa with dopa decarboxylase in periphery will lead to pass of dopa to brain where it converts to dopamine and so increase it's concentration

Complete :

4- cholinergic drugs , acetozolamide used in reducing IOP

5- Atropin cause sandy eye by reduction
of lacrimal secretions

[THE GOLDEN BOY]

شكراا ياعبدة كتير

بس عندى سؤال هى المقدمة اللى فى الاول دى هنعمل فيها
أية ؟؟ أصل أنا لسة مبدأتش

[Dina al sheshtawy]

thnX 3bdl ra7man

[a_fouda2]

شكراا ياعبدة كتير

بس عندى سؤال هى المقدمة اللى فى الاول دى هنعمل فيها
أية ؟؟ أصل أنا لسة مبدأتش

العفو يا محمد

المقدمة دي يا سيدي ملهاش غير حل واحد بس ...

تتذاكر

شفت بقى الحل بسيط ازاي .

و ابدأ من دلوقتي أحسن عشان المادة كبيرة و عشان تلحق تقراها تاني عشان تربط كل حاجة ببعضها
و مينفعش تذاكر كل جزء فيها مستقل لازم تربطها ببعض عشان تفهمها وتعرف تذاكرها

thnX 3bdl ra7man

العفو يا دينا ,

بالتوفيق ان شاء الله

[THE GOLDEN BOY]

شكراا يا عبدة كدة زى الفل كلة فانى يابنى