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السليدز اللي في ال ppt بتاع الglycolysis
من 66 ل 70
دكتور ممدوح شرحهم؟؟؟؟؟؟
لا اطمني مفيش زهايمر ولا حاجة
الدكتور مشرحهمش
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Bio friday sheets
Sheet 1
True and false:
1-in catabolism ,the body needs energy. (false)
2-glucose is transformed to pyruvate by glycolysis. (true)
3-enzymes half life is 7-10 hours. (false)
4-collagen is a fibrous protein. (true)
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Sheet 2
Complete
1- positive nitrogen balance is associated with growth hormone while negative nitrogen balance is associated with glucucorticoids hormone
2- during nitrogen mtabolism purines is converted into uric acid while pyrimidine is converted into urea which excreted in urine
3- anaerobic glycolysis terminates with lactate instead of pyruvate
4- hexokinase is distributed in all tissues while glucokinase is distributed in liver only
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Sheet 3
Choose :
- phosphpfructokinaseis the rate limiting enzyme of glycolysis
(Hexokinase- phosphpfructokinase- phsphoglyceratekinase)
-Lactate dehydrogenase converts pyruvate to lactate producing NAD+
(Lactate dehydrogenase- pyruvate dehydrogenase- pyruvate decarboxylase)
- Glycolysis in RBCs gives 1ATP
(1-2-6)
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Sheet 4
Complete the following :
1- Malonic acid is a competitive inhibitor of succinate dehydrogenase.
2- Insulin activates pyruvate DH , inhibits pyruvate carboxylase While Acetyl Co A inhibits pyruvate DH & activates pyruvate carboxylase
3- In the Second Phase of glycolysis , glyceraldahyde -3- phosphate is converted to pyruvate
4- Acetyl CoA Converted to Citrate by means of Citrate Syntase
5- Kreb’s cycle is inhibited by: Starvation , Diabetes mellitus , Anaerobic conditions
6- In the first five steps of glycolysis , One six -carbon molecule of glucose is split into two 3-carbon compounds
7- In kreb’s Cycle , 5 pairs of electron (from hydrogen atom of substrate ) to be used in ATP Productuon
8- The rate limiting enzyme of kreb's cucle is Citrate synthase
9- Arsenite inhibits Kreb’s cycle.
10- Mitochondrial isocitrate DH is NAD+linked, while cytoplasmic isocitrate DH is NADP+linked.
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Sheet 5
Complete :
1- malate + NADP+ malic enz pyruvate +CO2 + NADPH
The role of malic acid in this reaction is catalyzing the oxidative decarboxylation of malate to pyruvate .
2- pyruvate Ala(NH3)
In this reaction coenzyme is PLP which drived
From vit B6.
3- aspartate + alpha- ketoglutarate plp pmp oxaloacetate + glutamate .
This reaction done in liver.
Choose :
- Which of the following fragments cannot be converted directly into pyruvate?
(Alanine - Phosphoenolpyruvate - Lactate - Oxaloacetate - None of the above)
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Sheet 6 :
Complete :
1- The complete urea cycle occurs in liver
(liver-kidney-small intestine)
2- L-ornithine is converted to L-citrulline by reacting with carbamoyl phosphate
(L-aspartate - fumerate - carbamoyl phosphate)
3- and this reaction occurs in mitochondria
(cytoplasm- mitochondria- nucleus)
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Best wishes
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