لتصبح صيدلي محترف

[...مصر...]

الموضوع ده إن شاء الله هنتابع فيه معلومات كتيرة عشان نكون محترفين يا ريت كلنا نبحث ونشارك
بسم الله نبدأ
• Combining aspirin with a prescription blood thinner such as Plavix (clopidogrel) can cause excessive bleeding
Certain medications used to treat fungal infections can cause serious side effects when combined with cholesterol-lowering medications such as Lipitor(atorvastatin).
• The herbal supplement ginkgo bilboa can cause bleeding if taken with aspirin.


• Decongestants, such as pseudoephedrine found in many cough and cold preparations, can increase blood pressure and may be dangerous for people with hypertension.
• Beta blockers, such as Toprol XL (metoprolol) and Tenormin (atenolol), used to treat high blood pressure and certain types of heart disease can worsen the symptoms of asthmaand COPD.
• Diuretics, such as Hydrodiuril (hydrochlorothiazide), can increase blood sugar in people with diabetes.

Medications which should be
Taken with FOOD

Allopurinol
(take after meal)
Amiodarone
(Cordarone)
Carvedilol
(Coreg)
Cefpodoxime
(Vantin)
Felbamate
(Felbatol)
fenoprofen
Hydroxychloroquine
(Plaquenil)
Ketorolac
methanamine
Naproxen
Olsalazine
Piroxicam
Ritonavir
(Norvir)
Spironolactone
Ticlopidine
Valproic acid

Atovaquone
(Mepron)
Baclofen
(Lioresal)
Carbamazepine
(Tegretol)
Diclofenac
(Voltaren_
fenofibrate
(TriCor)
Griseofulvin
Indomethacin
Lithium
mebendazole
Nelfinavir
(Viracept)
Perphenazine
Potassium salts
Salsalate
Sulfasalazine
Tolmetin

Augmentin
Bromocriptine
(Parlodel)
Chloroquine
Divalproex sodium
(Depakote)
Fiorinal
glyburide (take with breakfast)
Iron preparations (Take between meals--if GI upset occurs take with food)
Metronidazole
methylprednisolone
Nitrofurantoin
Pentoxifylline
Prednisone
Saquinavir
Sulfinpyrazone
Trazodone

Aspirin
clofazimine
(Lamprene)
Cimetidine
(Tagamet)
Doxycycline
Fludrocortisone
Hydrocortisone
Itraconazole capsules
Misoprostol
(Cytotec)
naltrexone
Niacin
Pergolide
Procainamide
Sevelamer
(Renagel)
Sulindac
Troglitazone

[كليوباترا]

[egyptian and proud]

جزاكم الله خيرا علي المعلومات القيمه دي

[...مصر...]

Patients who take allopurinol in combination with the penicillin antibiotics amoxicillin or ampicillin may have skin rashes more frequently than they would if the drugs were not combinedn
Patients taking allopurinol should be aware that large doses of vitamin C may increase the possibility of kidney stone formation. In addition, large doses of vitamin B-3, also called niacin, may compromise the effectiveness of allopurinol and make the patient's gout condition more serious.


Aminoglycosides

Amikacin

Gentamicin

Kanamycin

neomycin

Tobramycin

Paromomycin




all this group with

furosemide

bu****nide


increase the ototoxicity


so other diuretics are used as

spironolactone



Cephalosporins

Cefaclor

Cefazolin

Cefoperazone

Cefotaxime

Cefpodoxime =Orelox

Cefprozil

Cefotriaxone

Cefuroxime =Zinnat

Cephadroxil

Cephalexin

Cephradine

Cephazolin

all this group with

Colistin = Colimex


Increase the risk of renal damage

Chloramphenicol

Thiamphenicol


with

Paracetamol


Potentiate agranulocytosis

So this combination should be avoided

خطأ شائع

[...مصر...]

Aminoglycosides + Amphotericin B
A number of patients developed nephrotoxicity, which was attributed to amphotericin
B. Raised gentamicin or amikacin levels, without significant changes in creatinine,
were seen in children treated with amphotericin

The serum levels of digoxin can be increased (more than doubled) by the concurrent
use of gentamicin in patients with congestive cardiac failure and diabetes

A reduction in serum aminoglycoside levels can occur if aminoglycosides and
penicillins are given together to patients with severe renal impairment. Carbenicillin,
piperacillin and ticarcillin have been implicated with both gentamicin and
tobramycin. Netilmicin appears not to interact with piperacillin. No interaction of
importance appears to occur either with intravenous aminoglycoside and penicillins
in those with normal renal function, or between aminoglycosides and carbapenems.
-----
There is some clinical evidence that amphotericin B given with either itraconazole,
ketoconazole or miconazole may possibly be less effective than amphotericin B given
alone, and the adverse effects may be greater


Amphotericin B and corticosteroids can cause potassium loss and salt and water
retention, which can have adverse effects on cardiac function.


Amphotericin B may cause hypokalaemia. Loop diuretics or thiazide and related
diuretics increase the risk of hypokalaemia when given with amphotericin

[...مصر...]

An aluminium/magnesium hydroxide-containing antacid reduced the AUC of
fexofenadine by about 40% in one study.
Although the clinical significance of this effect has not been assessed it is
recommended that administration is separated by 2 hours.


Antacids + Aspirin
The serum salicylate concentrations of patients taking large doses of aspirin or other salicylates as anti-inflammatory drugs can be reduced to subtherapeutic levels by
aluminium/magnesium hydroxide or sodium bicarbonate antacids.

Antidiabetics + Ketotifen
The concurrent use of biguanides (e.g. metformin) and ketotifen appears to be well
tolerated, but a fall in the number of platelets has been seen in one study in patients
taking the combination.

Cephalosporins + Warfarin and other oral
anticoagulants
Cephalosporins with an N-methylthiotetrazole side-chain can cause bleeding alone or
more severely in the presence of an anticoagulant. The cephalosporins implicated are
cefaclor, cefaloridine, cefalotin, cefamandole, cefazaflur, cefazolin, cefixime, cefmenoxime,
cef****zole, cefminox, cefonicid, cefoperazone, ceforanide, cefotetan,
cefotiam, cefoxitin, cefpiramide, ceftriaxone, and latamoxef

The absorption of tetracyclines is inhibited by up to 50% by zinc. All tetracyclines
(with perhaps the exception of doxycycline) are expected to interact similarly.
-----
ده رابط لتجميعة بسيطة لتداخلات الأدوية أتمنى يعجبكم
http://www.syrianclinic.com/syriancl...eractions.html

[الملاك الضاحك]

جزاك الله خيرا
متابعه مع حضرتك

[...مصر...]

جزانا وإياكم أنا عايزة مشاركاتكم كمان في الموضوع عشان كلنا نساعد بعض

[نعمة]

جزاكي الله خيرا متابعين إن شاء الله

[...مصر...]

جزانا وإياكم د نعمة
a total of 25 interactions were considered to be clinically important. They include:
benzodiazepines -- azole antifungals
carbamazepine -- propoxyphene
cyclosporine -- rifamycins
digoxin -- clarithromycin
ergot alkaloids -- macrolide antibiotics
oral contraceptives -- rifampin
ganciclovir -- zidovudine
methotrexate -- trimethoprim
nitrates -- sildenafil
pimozide -- macrolide antibiotics
pimozide -- azole antifungals
theophylline -- quinolones
theophylline -- fluvoxamine
thiopurines -- allopurinol
MAOI -- dextromethorphan
MAOI -- anorexiants
MAOI -- sympathomimetics
MAOI -- meperidine
MAOI -- SSRI
anticoagulants -- thyroid hormones
warfarin -- barbiturates
warfarin -- cimetidine
warfarin -- fibric acids
warfarin -- NSAIDs
warfarin -- sulfinpyrazone
-----
ممكن تحسوا إن الموضوع كبير وما تحفظوش اللي فات كويس بس الورقتين دول روعة ومهمين جدا جدا لأنها تداخلات ال otc اللي احنا بنطلعها من غير روشتة وكمان لأن الأدوية دي بنصرفها كتير جدا جدا .... لازم تحفظوا الورقتين دول كويس وإن شاء الله أعملكوا إمتحان فيهم
الورقتين هنزلهم من اللينك دي
http://www.mediafire.com/?1mzqf8ob4ngq3vx