أ.د / محمود بكر عميد الكلية الجديد
Mahmoud Bakr El-Ashmawy, Ph. D
PERSONAL
Citizenship: Egyptian
Birth: Feb. 5, 1954. Mansoura, Egypt
Address:Dept. of Medicinal Chemistry
Faculty of Pharmacy, Mansoura University
Mansoura 35516, Egypt.
Phone: 2-050-2247496 (W); 2-050-2365899 (H); 2-016-2344455 (Mobile).
Fax: 2050-2247496 (W)
E-mail: [email protected], [email protected]
EDUCATION
Ph. D. (1986), inMedicinal Chemistry, "Cum Laude", Universidad Complutense de Madrid, Spain. Dissertation: "Synthesis and preliminary pharmacological evaluation of thienylether derivatives: Thiophene analogues of certain pharmacodynamic agents".
M. Sc. (1982), inPharmaceutical Chemistry, University of Mansoura, Egypt. Dissertation: “Synthesis and screening of certain N-trityl derivatives as molluscicides."
B. Sc. (1977), inPharmaceutical Sciences, "Excellent with Honor", University of Mansoura, Egypt.
PROFESSIONAL EXPERIENCE: ACADEMIC POSITIONS
·Dec. 9, 2004: Chairman, Dept. of Medicinal Chemistry, Mansoura University, Egypt.
·July 26, 1998: Professor of Medicinal Chemistry, Mansoura University, Egypt.
·May 25, 1992: Associate Professor of Medicinal Chemistry, Mansoura University, Egypt.
·Feb. 23, 1987: Lecturer of Medicinal Chemistry, Mansoura University, Egypt.
PROFESSIONAL EXPERIENCE: SABBATICAL and FELLOWSHIPS
·Feb 07, March 07: Visiting Professor, Faculty of Pharmacy, Garyounis University, Libya.
·Feb 06, March 06: Visiting Professor, Faculty of Pharmacy, Garyounis University, Libya.
·Oct. 01-Aug. 03: Chairman, Dept. of Medicinal Chemistry, Al-Isra University, Jordan.
·Aug. 98-Sept 01: Professor of Medicinal Chemistry, Al-Isra University, Jordan.
·Oct. 96-July 98: Associate Professor of Medicinal Chemistry, Al-Isra University, Jordan.
·Apr. 96-June 96: Visiting Professor, Dept. of Med. Chem. University of Sana’a, Yemen.
·Aug. 93-Sept.94: Research Scientist, Medical College of Virginia, Richmond, VA, USA.
·July 89-June 91: Postdoctoral Fellow, Medical College of Virginia, Richmond, Virginia.
·Oct. 82-June 86: PhD student, Institute of Medicinal Chemistry, CSIC, Madrid, Spain.
PROFESSIONAL MEMBERSHIP
Administration
- Chairman, Board of Med. Chem. Department, Mansoura University, 2004-now
- Member, Faculty Council, Faculty of Pharmacy, Mansoura University, 2003-now.
- Member, University Council, Al-Israa University. 2000-2002
- Member of the Board of Faculty of Pharmacy, Al-Israa University, 1998-2003.
Members of different committee
- The Committee for higher education and research, 2005-now
- The Committee for education and student affairs, 2004-2006
- Member, Mansoura University Library Committee. 2005.
- Member of the Committee of Laboratories and Scientific Instruments, Mansoura University, 2004.
- Chairman of the Recruitment and Promotion Committee, Faculty of Pharmacy, Al-Israa University
- University Curriculum Committee, Al-Isra University 1999-2001
- University Committee of Scientific Research, Al-Isra University 1999-2001
- Al-Isra University Library Committee 1997
- Community service and environmental development committee, Mansoura University 1994-1996
Scientific / Professional Societies
- Referee in the Committee for Promotion in Pharmaceutical Chemistry, Supreme Council of Egyptian Universities,
- Member, Mansoura University Medical Research Ethics Committee
- Member, The Egyptian Pharmaceutical Society
- Member, The Egyptian Syndicate of Pharmacists
Advisory / Consultant Positions
- Consultant of Pharmaceutical Edudation for Al-Israa University, Amman, Jordan.
LANGUAGES
oArabic
oEnglish
oSpanish.
AWARDS
oUniversity of Mansoura Award in Medicinal Chemistry, Mansoura, Egypt, 1991.
oThe Third World Academy of Science Award in Medicinal Chemistry, Trieste, Italy, 1992.
QUALITY ASSURANCE
A) POSITIONS
a)Member, the establishment of the internal Quality Assurance System Project, Faculty of Pharmacy, Mansoura University.
b)Faculty Coordinator for the Mansoura University Development Center (UDC), 2005-june 2007.
c)Director of the Deveolpment and Performance Appraisal Unit, Faculty of Pharmacy.
d)Member of Quality Assurance and Accreditation Project Management Team, Faculty of Pharmacy.
e)Member of the Management and Excutive Teams of Mansoura University Strategic Plan.
B) FACULTY and LEADERSHIP DEVELOPMENTAL PROJECT (FLDP)
Attendance of FLDP programs that aim to improve the educational skills and the leadership skills within the University Faculty members
a)Human resources management (20 hrs), July 2005.
b)Administrative skills (20 hrs), August 2005.
c)Financial affairs (15 hrs), Sep 2005.
d)Quality assurances and accreditation (10 hrs), March 2006.
C) WORKSHOPS in QUALITY ASSURANCE
Participation, preparation and conduction of workshops in the Quality Assurance and Accreditation areas:
a)Workshop on the establishment of an internal Quality Assurance system at the faculty; Faculty of Pharmacy, Cairo University, Dec 2004.
b)Workshop on Program Specification and Report, Mansoura University, May 2005.
c)Peer review Workshop, Oct 21, 2006, Faculty of Agriculture, Cairo University.
d)Operational workshop on the Developmental Engagement, April 23, 2007, faculty of Agriculture, Cairo University.
e)Workshop on Follow-Up visits, April 26, 2007, Faculty of Agriculture, Cairo University.
f)Coordinator ofWorkshops and Training how to develop Course specification, Course report, Program specification and Program report
g)Preparation and participation in applying program for raising the awareness of pahrmacy students
D) PEER REVIEWER FOR THE DEVELOPMENTAL ENGAGEMENT SITE VISITSTHROUGH THE NATIONAL QUALITY ASSURANCE AND ACCREDITATION AGENCY (NQAAA), EGYPT
a)Peer Reviewer, Developmental engagement Site Visit to Faculty of Pharmacy, Al-Minia University, Nov 4-9, 2006
b)Peer Reviewer, Developmental engagement Site Visit to Faculty of Pharmacy, Ain-Shams University, April 29-May 2, 2007
c)Peer Reviewer, Developmental engagement Site visit to Faculty of Pharmacy, Suez Canal University, Oct 27-30, 2007
EDUCATION and EDUCATIONAL DEVELOPMENT
A) TEACHING EXPERIENCE
oStandard Medicinal Chemistry courses offered to undergraduate Pharmacy students.
oAdvanced Medicinal Chemistry courses for graduate students.
oDrug Design course for undergraduate and graduate students.
oBasic Pharmaceutical Organic Chemistry courses for undergraduate students.
oResearch techniques in Medicinal Organic Chemistry to new graduate students.
oCourse Coordinator for the Medicinal Chemistry and Drug design course offere to Fourth Year students.
oCourse Coordinator for editing of the theoretical and Practical Medicinal Chemistry and Drug Design contents for Pharmacy student.
B) EXTERNAL EXAMINER FOR MEDICINAL CHEMISTRY AND DRUG DESIGN COURSES
oInternal and external examiner for medicinal chemistry and drug design courses, at Departments of Medicinal Chemistry of Faculties of Pharmacy of egyptian universities:
Mansoura University, Alexandria University, , Ain-Shams University, , Al-Azhar University, , Cairo University, , Helwan University, , Al-Minia University, , Assiut University, , Suiz-Canal University, , Tanta University, , Zagazig University, , 6 October University, , Misr University of Science and Tecnology (MUST), Misr Internation University (MIU).
oExternal examiner for Medicinal Chemistry and Drug Design courses, at Faculties of Pharmacy of regional universities:
Garyounis University, Benghazi, Libia, Sept 2003; Al-Fateh University, Triboli, Libia, May 2005; Al-Fateh University, Triboli, Libia, June 2006; Al-Fateh University, Triboli, Libia, August 2007.
C) CURRICULUM DEVELOPMENT AND IMPROVING PHARMACY EDUCATION
- Member of the triplicate committee for the Final exams of Medicinal Chemistry in Faculties of Pharmacy in the Egyptian Universities; Decree of the President of the Universities Supreme Council 28-2006.
- Member of the Curriculum Development Committee, Faculty of Pharmacy, Mansoura University.
- Coordinator of the Examination Paper Evaluation Committee, Faculty of Pharmacy, Mansoura University.
- Coordinator of workshops and training sessions for staff on the development of Course specification, Course report, Program specification and Program report
- Preparation and participation in seminars and meetings for raising the awareness of pahrmacy students in Quality assurance and Educational Deveolpment.
- Chairman, Faculty of Pharmacy Curriculum Committee, Al-Isra University, Amman, Jordan, 1999-2003
- Mamber, University Curriculum Committee, Al-Isra University, Amman, Jordan, 1999-2001
- Chairman, University Curriculum Committee, Al-Isra University, Amman, Jordan, 2002
- Installment of the electronic courses of Medicinal Chemistry on the internet.
RESEARCH AND OTHER SCHOLARLY AND SCIENTIFIC ACTIVITIES:
A) RESEARCH INTEREST
oSynthesis and structural elucidation of new organic and heterocyclic compounds.
oDesign and synthesis of potentially active chemotherapeutic agents.
oApplication of Molecular modeling techniques in the development of selective ligands for the CNS receptor system.
oInterpretation of the binding data and biological activity in terms of Structure-Activity Relationship.
B) RESEARCH PROJECTS
oPrincipal Invistigator of a common research project that engage three academic departments at Faculty of Pharmacy, Mansoura University, entitled: Design and Synthesis of new Curcumin analogues as anticancer agents.
C) SUPERVISION OF THESIS
a)Ph.D. Thesis (1995), Eman R. El-Bendary, Faculty of Pharmacy, Mansoura University.
b)Ph.D. Thesis (1995), Laila A. Abou-Zeid, Faculty of Pharmacy, Mansoura University.
c)M.Sc, Thesis (1995), Sahar A. Abo el-Magd, Faculty of Pharmacy, Mansoura University.
d)Ph.D. Thesis (2006), Ghada S. H. Hassan, Faculty of Pharmacy, Mansoura University.
e)M.Sc, Thesis (not yet), Hazem A. Ghabbour, Faculty of Pharmacy, Mansoura University.
f)Ph.D. Thesis (not yet), Mariam A. Ghali Saed, Faculty of Pharmacy, Mansoura University.
g)Ph.D. Thesis (not yet), Ibrahim M. Eldeeb, Faculty of Pharmacy, Mansoura University.
h)Ph.D. Thesis (not yet), Nadia S. El-sayed, Faculty of Pharmacy, Mansoura University.
D) REFEREE IN PERIODICALS
a)Medicinal Chemistry Research (USA), 1993, 1994
b)Jordanian Journal of Applied Science, University of Applied Science; Amman, Jordan, 2002, 2003.
c)Mansoura Journal of Pharmaceutical sciences, Mansoura University, Dec 2004, Nov 2005, April 2006
d)Bulletin Faculty of Pharmacy, Cairo University; Nov. 2005
e)Bulletin of Pharmaceutical sciences, Assiut University, May 2006, Dec 2006, May 2007.
f)Egyptian Journal of Biomedical Sciences, Al-Azhar University, August 2006.
E) REFEREE IN PROMOTION COMMITTEE
a)The Scientific Committee for Promotion in Pharmaceutical Chemistry, Jordan; University of Philadelphia. 2003. Dr. Mowaffag Badawneh
b)The Scientific Committee for Promotion in Pharmaceutical Chemistry, (Associate Professors) USC, Egypt; Cairo University, 2005. Dr. Amal Abdel-Halim Eisa
c)The Scientific Committee for Promotion in Pharmaceutical Chemistry, (Full Professors), USC, Egypt; Cairo University, Jan 2006. Prof. Dr. Ashraf M Abbady
d)The Scientific Committee for Promotion in Pharmaceutical Chemistry, (Associate Professors) USC, Egypt; Cairo University, Nov 2006. Dr. Gihan Hegazy Yousef
e)The Committee for Promotion in Pharmaceutical Chemistry, Ajman, United Arab Emirates. March 2007. Prof. Dr. Omar Ali Attef
f)The Scientific Committee for Promotion in Pharmaceutical Chemistry, (Associate Professors) USC, Egypt; Cairo University, Sept 2007. Dr. Amal Mamdouh Yousef
F) REFEREEING of M.SC. and PH.D. THESIS: Member of the COMMITTEE-IN-CHARGE
a)Ashraf A. Abd El-Rahman; Ph.D. Thesis, Al-Azhar University, 1995
b)Laila A. Abou-Zeid; Ph.D. Thesis, Mansoura University, 1995
c)Sahar A. Abo el-Magd; M.Sc. Thesis, Mansoura University, 1995
d)Gamal A. Abou-Rahmah; Ph.D. Thesis, Al-Minia University, 2004
e)Mariam A. Ghali; M.Sc. Thesis, Mansoura University, 2005
f)Mohammad Abo El-Hassan; M.Sc. Thesis, Suez Canal University, 2005
g)Marwa Y. Sayed Ahmad; M.Sc. Thesis, Al-Azhar University, 2005
h)Mona H Badr; Ph.D. Thesis, Alexandria University, 2006
i)Mohammad El-Saady; M.Sc. Thesis, Cairo University, 2006
j)Ibrahim M. Eldeeb; M.Sc. Thesis, Mansoura University, 2006
k)Mahmoud M. Moustafa; M.Sc. Thesis, Al-Azhar University, 2006
l)Mohammad El-Sanee; M.Sc. Thesis, Assiut University, 2006
m)Ghada S. H. Hassan; Ph.D. Thesis, Mansoura University, 2007
n)Rania H. Badawy; M.Sc. Thesis, Zagazig University, 2007
o)Abdurrahman Salah, M. Sc. Thesis, Al-Azhar University, 2007.
p)Amira I. Ali Khalil, M. Sc. Thesis, Ain-Shams University, 2007.
q)Ola N. El-Samaloty, M. Sc. Thesis, Al-Azhar University, 2007.
r)Noha H. A. Metry, M.Sc. Thesis, Cairo University, 2007
G) REFEREEING M.SC. and PH.D. THESIS: (INSPECTION ONLY)
a)Rizk R. Ayyad; Ph.D. Thesis, Al-Azhar University, 2005
b)Ola A. Maher; Ph.D. Thesis, Mansoura University, 2006
c)Dalia H. Soliman; Ph.D. Thesis, Al-Azhar University, 2007
H) REFEREEING SCIENTIFIC PROJECTS
a)Project introduced to Kind Saud University.
دراسة كيمياء الفرمونات وتشييد مشتقات حديثة منها وتجربتها لمكافحة سوسة النخيل الحمراء في المملكة العربية السعودية
I) CONFERENCES and MEETINGS
oAttendance of more than 15 Pharmaceutical Conferences and Meetings in different countries
Egypt, (1994, 1995, 2002, 2004),
Spain (1983), Sweden (1984),
USA (1990, 1991, 1994), Jordan (1997, 1998, 1999, 2000, 2002),
Syria (1997) Yemen (1996),
Tunisia (2000) United Arab Emirates (2002).
oChairman of a scientific session at the 6th Scientific Congress of the Associaton of Colleges of Pharmacy in the Arab World; Ajman, United Arab Emirates. October 19-21, 2002.
oInvited speaker of a plenary lecture entitled (Pharmaceutical Education and relevance to Pharmacy Practice) at the inauguration the The Fourth Conference for the Arab Colleges of Pharmacy, Monastir, Tunisia, November 2000.
J) PUBLICATIONS,
o35 publications in international and national journals in the field of Medicinal chemistry: Examples of the International Journals:
Journal of Medicinal Chemistry,
European Journal of Medicinal Chemistry;
Medicinal Chemistry Research,
Bioorganic Medicinal Chemistry Letters
Monatsh Chemie,
Arzneim Forsch,
il Farmaco,
Arch Pharm Med Chem,
SELECTED PUBLICATIONS
- Corral C, El-Ashmawy MB, Lissavetzky J, Madronero R, Darias V, Martin D, Estevez E. Synthesis and b-adrenoceptor blocking activity of thiophenic analogues of tolamolol. Eur. J. Med. Chem. 1985, 20, 133-136.
- Corral C, El-Ashmawy MB, Lissavetzky J, Bravo L, Darias V, Martin D. Synthesis and evaluation of thiophene analogs of lotucaine. Il Farmaco, Ed. Sci. 1987, 42, 267-275.
- Corral C, El-Ashmawy MB, Lissavetzky J, Manzanares I. "Reactions of methyl 3-hydroxythiophene-2-carboxylate. Part 4. Synthesis of methyl 5-azolyl-3-hydroxy thiophene-2-carboxylates". J. Heterocyclic Chem., 1987, 24, 1301-1303.
- El-Emam AA, Moustafa MA, El-Subbagh HI, El-Ashmawy MB. Triazoles and fused triazoles III. Facile and efficient synthesis of 2,5-disubstituted s-triazolo [3,4-b]-1,3,4-thiadiazoles. Monatsh. Chemie, 1990, 121, 221-225.
- El-Ashmawy MB, Lissavetzky J, Darias V Martin D. Synthesis and pharmacological study of a thiophene analogue of moprolol and related compounds. Arch. Pharm. (Weinheim)1991, 324, 45-48.
- El-Ashmawy MB, Shehata IA, El-Subbagh HI El-Emam AA. Fused Pyrimidines. Synthesis of Pyrazolo [3,4-d]-1,3,4-thiadiazolo [3,2-a] pyrimidine and pyrazolo [3,4-d] pyrimidino [2,1-b] benzothiazole derivatives. Gazz. Chim. Italiana, 1991, 121, 113-115.
- Glennon RA, Smith JD, Ismaiel AM, El-Ashmawy MB, Battaglia G, Fischer JB. Identification and exploitation of the sigma opiate pharmacophore. J. Med. Chem. 1991, 34. 1094-1098.
- Glennon RA, El-Ashmawy MB, Fischer JB, Burke-Howei KJ, Ismaiel AM. N-Substituted 5-phenylpentylamines: new class of sigma ligands. Med. Chem. Res., 1991, 1, 207-212.
- Ablordeppey SY, El-Ashmawy MB, Glennon RA. Analysis of the structure-activity relationships of sigma receptor ligands. Med. Chem. Res. 1991, 1, 425-438.
- El-Ashmawy M, Ablordeppey SY, Gad L, Issa H, Fischer JB, Burke-Howei KJ, Glennon RA. Further investigation on 5-phenylpentylamine derivatives as novel sigma receptor ligands. Med. Chem. Res. 1992, 2, 119-126.
- El-Ashmawy MB, Zedan HA. Synthesis and molluscicidal activity of new benzothiophene-2-carboxanilide derivatives. Med. Chem. Res. 1994, 4, 315-322.
- Glennon RA, Ablordeppey SY, Ismaiel AM, El-Ashmawy MB, Fischer JB, Burke-Howie K. Structural features important for sigma-1 receptor binding. J. Med. Chem., 1994, 37, 1214-1219
- El-Ashmawy MB. Synthesis and antimicrobial evaluation of certain derivatives of 2-pyrimidinone, 2-pyrimidinethione and 2-thioxo-4,6-pyrimidinedione. Saudi Pharm. J. 1997, 5, 156-161.
- Ablordeppey SY, El-Ashmawy MB, Fischer JB, Glennon RA. A CoMFA investigation of sigma receptor binding affinity: Reexamination of a spurious sigma ligand. Eur. J. Med. Chem. 1998, 33, 625-633.
- El-Ashmawy MB. The role of natural antioxidants and synthetic nonsteroidal anti-inflammatory drugs in the chemoprevention of cancer. (Review Article). Saudi Pharm.J. 1999, 7, 1-13.
- Abou-Zeid LA, El-Mowafy AM, El-Ashmawy MB, Hendry LB, Abdelal AM, Badria FA. Novel piperidinedione analogs as inhibitors of breast cancer growth. Arch. Pharm. 2000, 333, 431-434.
- Glennon RA, Ismaiel A, Ablordeppey S, , El-Ashmawy M, Fischer Thioxanthene-derived analogs as sigma(1) receptor ligands. Bioorg Med Chem Lett. 2004; 14, 2217-2220.
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