answers
1-
*prescription require compounding or admixure
*prescription not require compounding -prefabricated
وممكن نقول معاهم الـOTC
2-
a)receptor
b)diluent-fillers
c)adhesive
3
pharmaceutical equivalents
drug products identical in the primary characters
-the same active ingredients with the same salt or ester
-same concentration of drug
-same dosage form
-same route of administration
but they may duffer in secondary characters ex:color &shape &packaging & expiration date
bio equivalent drug products
they are pharmaceutical equivalents whose rate and extend of absorption are not significantly different
when given with the same dose
4-
Harmless
don't interfee with the therapeutically activityof drug
don't interfere with assay tests
5-
It must remain clear when cooled to 10 c to ensure stability in storage under refrigeration
free from paraffin oil
the fluidity depends on the ratio between the unsaturated fatty acid to saturated
must comply the official requirements (saponification number &iodine number )
No rancidity no change in odor or taste
6-
advantages:
inert has no pharmacological effect
safe non toxic
palatable
large solvent capacity
available and inexpensive
disadvantages:
some drugs are hydrolyzed in water forming toxic byproducts
difficult to be purified
some drugs have poor solubility in water
sheets
المشاركة الأصلية كتبت بواسطة نور عمرو
